教育背景
2015.09-2020.06 中山大学 材料物理与化学 工学博士
2011.09-2015.06 广东工业大学 高分子材料与工程 工学学士
工作履历
2025.12至今，beat365在线唯一官网，副教授/博士生导师
2022.10 至 2025.08，南方医科大学，博士后
2020.08 至 2022.08，中山大学，博士后
科研工作
【学术表现】
从事生物医用材料的研究，主要围绕纳米材料和水凝胶材料的生物医学应用进行研究探索。在本研究领域以第一作者和通讯作者（含共同）发表学术论文十余篇，包括Science Advances 和 Advanced Materials 等国际权威期刊。申请并获授权国家发明专利5项。主持国自然青年基金和多项省部级项目。
【主要论著】
1. Shaohui Deng#, Lijun Hu#, Guo Chen#, Jujian Ye, Zecong Xiao, Tianwang Guan, Shuai Guo, Wei Xia, Du Cheng, Xiaochun Wan*, Ke Cheng*, Caiwen Ou*, A PD-L1 siRNA-loaded boron nanoparticle for targeted cancer radiotherapy and immunotherapy. Advanced Materials, 2025, 37: e2419418.
2.Shaohui Deng#, Xiaoxia Li#, Shuang Liu, Jifeng Chen, Sing Yian Chew, Mingqiang Li, Kam Leong*, Du Cheng*, Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects. Science Advances, 2020, 6: eabb4005.
3. Shuai Guo#, Tianwang Guan#, Yushen Ke#, Yuping Lin, Rundong Tai, Jujian Ye, Zhilin Deng, Shaohui Deng*, Caiwen Ou*, Biologically logic-gated Trojan-horse strategy for personalized triple-negative breast cancer precise therapy by selective ferroptosis and STING pathway provoking. Biomaterials, 2025, 315: 122905.
4. Xinghua Huang#, Jianwei Li#, Guanyi Li, Binyu Ni, Ziji Liang, Haodong Chen, Chaozhang Xu, Jianhua Zhou*, Jinsheng Huang*, and Shaohui Deng*, Cation-free siRNA-cored nanocapsules for tumor-targeted RNAi therapy. Acta Biomaterialia, 2023, 161:226-237.
5. Xinyao Zheng#,Shaohui Deng#*, Yuan Li#, Zhipeng Luo#, Ziqi Gan#, Zhaoping Zheng, Rui Xu, Shan Xiao, Yuxiong Cai, Jianfu Meng, Li Li, Changxing Li, Xiaowen Xue, Wei Dai, Si Qin, Mengying Wang, Kang Zeng*, Zecong Xiao*, Laixin Xia*, Targeting m6A demethylase FTO to heal diabetic wounds with ROS-scavenging nanocolloidal hydrogels. Biomaterials, 2025, 317: 123065.
6. Shaohui Deng#, Shiyin Wang#, Zecong Xiao*, Du Cheng*, Unprotonatable and ROS-sensitive nanocarrier for NIR spatially activated siRNA therapy with synergistic drug effect. Small, 2022, 18(41): e2203823.
7. Guo Chen#, Shaohui Deng# *, Shubo Liu, Yuexin Zhao, Yuanqiang Xiao, Xiangming Zeng, Yafei Xu, Du Cheng* and Bin Chen*, pH and ROS Dual-Sensitive nanocarriers for the targeted co-delivery and on-demand sequential release of tofacitinib and glucosamine for synergistic rheumatoid arthritis treatment. Small, 2024, 20: e2308520.
8. Guangman Cui#, Shaohui Deng#, Biao Zhang, Manchun Wang, Zhousheng Lin, Xinyue Lan, Zelong Li, Guangyu Yao*, Meng Yu*, and Jun Yan*, Overcoming the tumor collagen barriers: A multistage drug delivery strategy for DDR1-mediated resistant colorectal cancer therapy. Advanced Science, 2024, 11: e2402107.
9. Guo Chen#, Shaohui Deng#, Mingxiang Zuo#, Jin Wang, Du Cheng*, Bin Chen*, The synergistic effect of a non-viral CRISPRa system targeting VEGF-A and TGF-β1 on osteogenesis of pre-osteoblasts implanted with dual-crosslinked hydrogel. Materials Today Bio, 2022, 16: 100356.
10. Shuang Liu#, Shaohui Deng#, Xiaoxia Li, Jifeng Chen, Yaochang Yuan, Hanjun Zhao, Jie Zhou, Jin Wang, Hui Zhang, Du Cheng*, Endosomal escapable and nuclear localizing cationic polyaspartate-based CRISPR activation system for preventing respiratory virus infection by specifically inducing interferon-λ. ACS Appl Mater Interfaces, 2022, 14: 55376.
11. Lijun Hu#, Tan Li#, Shaohui Deng#, Honglin Gao, Yujie Jiang, Qiu Chen, Hui Chen, Zecong Xiao*, Xintao Shuai*, Zhongzhen Su*, Tertiary lymphoid structure formation induced by LIGHT-engineered and photosensitive nanoparticles-decorated bacteria enhances immune response against colorectal cancer. Biomaterials, 2024, 314: 122846.
【主持科研项目】
1.国家自然科学基金青年项目
2.广东省自然科学基金面上项目
3.广东省自然科学基金联合基金培育项目
4.广东省自然科学基金联合基金青年项目
5.博士后基金面上项目
6.博士后特别资助
学生/博后需求
欢迎本科生来实验室学习；欢迎硕士生、博士生报考；
所在侯仰龙教授团队长期招聘生物材料方向博士后。